| Factor | Amprolium | Toltrazuril |
|---|---|---|
| Regulatory status | OTC in most regions | Rx‑only (many countries) |
| Egg withdrawal | 0 h (labelled products) | 96 h |
| Meat withdrawal | 24 h poultry / 5 d cattle | 8 d poultry |
| Mode of action | Thiamine analogue | Mitochondrial respiration inhibitor |
| Cost per 100 kg BW | $$ | $$$$ |
Bottom line: Use Amprolium for everyday outbreaks and prevention; reserve Toltrazuril for resistant cases or when a broad‑spectrum protozoacide is mandated by your vet.