Amprolium Dosage Calculator
Get precise, species-specific amprolium dosing recommendations based on scientific guidelines and veterinary standards.
Calculate Your Dose
Select your animal species and enter the required information to receive accurate dosing recommendations.
How to Use This Calculator
1️⃣ Select Your Animal
Choose from chickens, turkeys, cattle, goats, sheep, or rabbits. Each species has specific dosing requirements based on body weight and water consumption patterns.
2️⃣ Enter Weight or Flock Size
For individual animals (cattle, goats, sheep), enter body weight. For flocks (chickens, turkeys), enter number of birds. For rabbits, choose between individual or group dosing.
3️⃣ Review Dosing Recommendations
The calculator provides precise measurements for water-based or oral drench administration, including duration of treatment and daily amounts.
4️⃣ Follow Safety Guidelines
Always observe withdrawal times before slaughter or egg/milk consumption. Follow with thiamine (vitamin B1) supplementation after treatment.
Understanding Amprolium Dosing
Water-Based Administration
Most amprolium treatments are administered through drinking water at concentrations of 125 mg/L (0.012-0.024%) for poultry and rabbits. This method ensures:
- ✓ Consistent daily intake based on natural drinking behavior
- ✓ Easy flock-wide treatment without individual handling
- ✓ Reduced stress compared to individual dosing
- ✓ Self-regulating intake as animals recover
Oral Drench Method
Ruminants (cattle, goats, sheep) typically receive amprolium via oral drench at 10 mg/kg body weight. This approach provides:
- • Precise individual dosing for accurate treatment
- • Guaranteed drug delivery regardless of water intake
- • Better control in severely affected animals with reduced drinking
- • Ability to treat individual valuable breeding stock
Treatment Duration
Common Dosing Mistakes to Avoid
Underdosing
Problem: Using concentrations below 125 mg/L or dosing <10 mg/kg reduces efficacy and prolongs recovery.
Solution: Always use our calculator for accurate concentrations based on current guidelines.
Overextending Treatment
Problem: Treating beyond 7 days risks thiamine deficiency (neurological symptoms, weakness, loss of appetite).
Solution: Limit to 5-7 days and always follow with vitamin B supplementation.
Ignoring Water Consumption
Problem: Not accounting for age, temperature, or health status affecting water intake leads to inconsistent dosing.
Solution: Monitor water consumption daily and adjust concentration if intake changes significantly.
Premature Treatment Cessation
Problem: Stopping treatment when symptoms improve (day 2-3) allows parasite lifecycle to continue.
Solution: Complete full 5-7 day course even if animals appear recovered.
Inaccurate Measurements
Problem: Eyeballing powder measurements or using incorrect concentration units leads to dosing errors.
Solution: Use precise scales (gram-level accuracy) and follow calculator measurements exactly.
Skipping Withdrawal Times
Problem: Not observing species-specific withdrawal periods before slaughter or consuming eggs/milk.
Solution: Follow FDA/regulatory withdrawal times: 24h (poultry), 5 days (cattle), check local regulations.
Species-Specific Dosing Considerations
Poultry (Chickens & Turkeys)
- Age Most vulnerable 2-12 weeks; adjust water concentration if chicks drink less
- Heat Hot weather increases water intake 2-3x; may need to reduce concentration
- Withdrawal 24 hours for meat, 0 days for eggs (approved in laying hens)
- Mixing Dissolve powder in small amount of warm water first, then dilute to final volume
Cattle
- Route Oral drench preferred; can mix in milk replacer for calves
- Weight Accurate weight critical for oral dosing; use livestock scale or weight tape
- Withdrawal 5 days for meat, 24 hours for milk (check local dairy regulations)
- Severity Severe cases may need supportive fluids and electrolytes alongside amprolium
Goats & Sheep
- Extra-Label Often extra-label use; consult veterinarian for compliance in your region
- Dosing 10 mg/kg oral drench daily; body weight estimation more critical than cattle
- Kids/Lambs Most susceptible 3-6 months; can mix in milk for nursing animals
- Withdrawal Typically 5 days meat, but verify local regulations for small ruminants
Rabbits
- Concentration Lower dose (0.012 mg/kg) reflects smaller body size and different pharmacokinetics
- Hepatic Form E. stiedae (liver coccidiosis) may require extended 10-14 day treatment
- Water Ensure fresh medicated water daily; rabbits sensitive to taste changes
- Withdrawal Not established officially; recommend 7-10 days for meat production
Quick Reference: Dosing Summary
| Species | Concentration | Route | Duration | Withdrawal (Meat) | Post-Treatment |
|---|---|---|---|---|---|
| Chickens | 125 mg/L (0.012%) | Drinking water | 5-7 days | 24 hours | Thiamine supp. |
| Turkeys | 125 mg/L (0.024%) | Drinking water | 5-7 days | 24 hours | Thiamine supp. |
| Cattle | 10 mg/kg BW | Oral drench/milk | 5 days | 5 days | Thiamine supp. |
| Goats | 10 mg/kg BW | Oral drench | 5-7 days | 5 days* | Thiamine supp. |
| Sheep | 10 mg/kg BW | Oral drench | 5-7 days | 5 days* | Thiamine supp. |
| Rabbits | 0.012 mg/kg | Drinking water | 7-14 days** | Not established | Thiamine supp. |
* Extra-label use in small ruminants may have different requirements in your region
** Hepatic coccidiosis (E. stiedae) may require extended treatment duration
BW = Body Weight | supp. = supplementation
⚠️ Critical Safety Guidelines
Thiamine Deficiency Risk
Not a Substitute for Diagnosis
Withdrawal Time Compliance
Environmental Management
Related Resources
Treatment Guides
Species-specific protocols with symptoms, prevention, and management strategies.
About Coccidiosis
Understand the disease, lifecycle, symptoms, and diagnosis of Eimeria infections.
How Amprolium Works
Molecular mechanism, pharmacokinetics, and scientific rationale for dosing protocols.
Frequently Asked Questions
No. Young animals (chicks, calves, kids, lambs) may drink less water per body weight, requiring concentration adjustments. For oral dosing in ruminants, always dose by body weight (10 mg/kg), not by age. Young poultry may need slightly higher water concentrations if they're drinking less than expected.
Taste aversion is rare with amprolium but can occur. Try dissolving powder in small amount of warm water first to improve dissolution. For poultry, ensure no other water sources are available. For ruminants experiencing severe dehydration, switch to oral drench method to guarantee drug delivery.
Use a digital scale with at least 1-gram precision. Do NOT use volume measurements (cups, tablespoons) as powder density varies. For liquid amprolium solutions, follow label concentration and use graduated cylinders or syringes for precise volume measurement.
Yes, for water-based administration. Hot weather can double or triple water consumption, leading to overdosing. Monitor daily water intake and reduce concentration proportionally if consumption increases significantly (>50% above normal). Maintain total daily amprolium intake at recommended levels.
Provide vitamin B complex or thiamine (B1) at 5-10 mg/kg body weight for 3-5 days after completing amprolium treatment. For poultry, add water-soluble vitamin supplements to drinking water. For ruminants, injectable B-complex is effective. This prevents delayed neurological symptoms from thiamine deficiency.
Low-dose amprolium (25-50 mg/L) is sometimes used prophylactically in high-risk situations (young animals, known contamination). However, this practice can delay natural immunity development and promote drug dependence. Prevention through biosecurity and management is superior to continuous prophylactic medication.
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